Here are some panel drawings from Milton Caniff to explain how composition effects story in cartooning:

“Here are two panels Milton Caniff drew to illustrate this business of composition for cartoonists. In the first he drew the scene in detail, spelling everything out pictorially. In the second panel most of the detail was omitted, leaving just enough to get the idea across. Also, moving the camera right up behind the rifleman’s shoulder puts the reader closer to the action, and gives him that important feeling of participation. Both panels are well composed, but the second is much better for the purpose. The important thing is to add power and clarity to the story. In case your Russian is rusty, the balloon reads: (The Americans have taken the city – this way!)”

–1950′s Famous Artists Cartoon Course – Lesson 11 Pg 14